|Application ||WB, IHC-P, E|
|Calculated MW||35853 Da|
|Dilution||ELISA (1:20000), IHC-P (20 µg/ml), WB (1:500 - 1:1000),|
|Other Names||AKR1B1, Aldose reductase, ALDR1, ADR, Aldehyde reductase, Aldehyde reductase 1, ALR2, Lii5-2 CTCL tumor antigen, Low Km aldose reductase|
|Target/Specificity||AKR1B1 Antibody detects endogenous levels of total AKR1B1 protein.|
|Reconstitution & Storage||PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.|
|Precautions||AKR1B1 / Aldose Reductase Antibody (aa241-290) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.|
|Tissue Location||Highly expressed in embryonic epithelial cells (EUE) in response to osmotic stress.|
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
Bohren K.M.,et al.J. Biol. Chem. 264:9547-9551(1989).
Chung S.,et al.J. Biol. Chem. 264:14775-14777(1989).
Graham A.,et al.Nucleic Acids Res. 17:8368-8368(1989).
Grundmann U.,et al.DNA Cell Biol. 9:149-157(1990).
Nishimura C.,et al.J. Biol. Chem. 265:9788-9792(1990).
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