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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ATP2A1 / SERCA1 Antibody (aa548-597)   

ATP2A1 / SERCA1 Antibody (aa548-597)

Rabbit Polyclonal Antibody

  • IHC - ATP2A1 / SERCA1 Antibody (aa548-597) ALS16547
    Anti-ATP2A1 / SERCA1 antibody IHC staining of human skeletal muscle.
  • WB - ATP2A1 / SERCA1 Antibody (aa548-597) ALS16547
    Western blot of extracts from HT-29/A549/NIH-3T3 cells, using ATP2A1 Antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O14983
Other Accession 487
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 110252 Da
Dilution ELISA (1:10000), IHC-P (10 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 487
Other Names ATP2A1, SERCA1, ATP2A, Calcium pump 1, SR Ca(2+)-ATPase 1
Target/Specificity ATP2A1 Antibody detects endogenous levels of total ATP2A1 protein.
Reconstitution & Storage PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.
PrecautionsATP2A1 / SERCA1 Antibody (aa548-597) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATP2A1
Function Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Skeletal muscle, fast twitch muscle (type II) fibers
Volume 50 µl
Research Areas
Citations (0)

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This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.


Zhang Y.,et al.Genomics 30:415-424(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Martin J.,et al.Nature 432:988-994(2004).
Daiho T.,et al.J. Biol. Chem. 276:32771-32778(2001).
Odermatt A.,et al.Hum. Genet. 106:482-491(2000).

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$ 395.00
Cat# ALS16547
(40 western blots)
Availability: 5 days
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