|Application ||WB, IHC-P, IF|
|Calculated MW||23292 Da|
|Dilution||IF (1:50 - 1:200), IHC-P (5 µg/ml), WB (1:500 - 1:1000),|
|Other Names||CLDN6, Claudin-6, Claudin 6, Skullin|
|Target/Specificity||Human CLDN6 / Claudin 6|
|Reconstitution & Storage||PBS, pH 7.2, 0.05% sodium azide. Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.|
|Precautions||CLDN6 / Claudin 6 Antibody (Val118) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a major role in tight junction-specific obliteration of the intercellular space (By similarity). May act as a coreceptor for HCV entry into hepatic cells.|
|Cellular Location||Cell junction, tight junction. Cell membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines|
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Plays a major role in tight junction-specific obliteration of the intercellular space (By similarity). May act as a coreceptor for HCV entry into hepatic cells.
Keen T.J.,et al.Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
Troy T.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Otsuki T.,et al.DNA Res. 12:117-126(2005).
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