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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   LEMD3 / MAN1 Antibody (C-Terminus)   

LEMD3 / MAN1 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

  • IHC - LEMD3 / MAN1 Antibody (C-Terminus) ALS16611
    Anti-LEMD3 / MAN1 antibody IHC staining of human kidney.
  • IF - LEMD3 / MAN1 Antibody (C-Terminus) ALS16611
    Immunofluorescence of LEMD3 in human colon tissue with LEMD3 antibody at 5 µg/mL.
  • WB - LEMD3 / MAN1 Antibody (C-Terminus) ALS16611
    Western blot analysis of LEMD3 in human colon tissue lysate with LEMD3 antibody at 1 ug/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y2U8
Other Accession 23592
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 99997 Da
Dilution IF (5 µg/ml), IHC-P (5 µg/ml), WB (1 µg/ml),
Additional Information
Gene ID 23592
Other Names LEMD3, MAN1, LEM domain containing 3
Target/Specificity Human LEMD3. At least three isoforms of LEMD3 are known to exist; this antibody will detect all isoforms. LEMD3 antibody is predicted to not cross-react with LEMD1 and LEMD2
Reconstitution & Storage PBS, 0.02% sodium azide. Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsLEMD3 / MAN1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LEMD3
Synonyms MAN1
Function Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest.
Cellular Location Nucleus inner membrane; Multi-pass membrane protein
Tissue Location Heart, brain, placenta, lung, liver and skeletal muscle
Research Areas
Citations (0)

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Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest.


Lin F.,et al.J. Biol. Chem. 275:4840-4847(2000).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Hellemans J.,et al.Nat. Genet. 36:1213-1218(2004).
Lin F.,et al.Hum. Mol. Genet. 14:437-445(2005).
Pan D.,et al.J. Biol. Chem. 280:15992-16001(2005).

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$ 395.00
Cat# ALS16611
(40 western blots)
Availability: 5 days
Bulk Size
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