|Application ||WB, IHC-P, IF|
|Calculated MW||45333 Da|
|Dilution||IF (1:100), IHC-P (10 µg/ml), WB (1:500 - 1:2000),|
|Other Names||GOLM1, BA379P1.3, Golgi membrane protein GP73, Golgi phosphoprotein 2, Golgi protein, 73-kD, gp73, GOLPH2, PSEC0257, C9orf155, Golgi membrane protein 1|
|Target/Specificity||Human GP73 / GOLPH2|
|Reconstitution & Storage||PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing.|
|Precautions||GOLM1 / GP73 / GOLPH2 Antibody (clone 6C9) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Unknown. Cellular response protein to viral infection.|
|Cellular Location||Golgi apparatus, cis-Golgi network membrane; Single-pass type II membrane protein. Note=Early Golgi. Cycles via the cell surface and endosomes upon lumenal pH disruption|
|Tissue Location||Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen Predominantly expressed by cells of the epithelial lineage Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), it is strongly expressed in hepatocytes-derived syncytial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Unknown. Cellular response protein to viral infection.
Kladney R.D.,et al.Gene 249:53-65(2000).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Otsuki T.,et al.DNA Res. 12:117-126(2005).
Puri S.,et al.Traffic 3:641-653(2002).
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