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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   CD4 Antibody (clone 5D9)   

CD4 Antibody (clone 5D9)

Mouse Monoclonal Antibody

  • IHC - CD4 Antibody (clone 5D9) ALS16661
    Anti-CD4 antibody IHC staining of human spleen.
  • WB - CD4 Antibody (clone 5D9) ALS16661
    HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CD4...
  • WB - CD4 Antibody (clone 5D9) ALS16661
    Western blot of extracts (35 ug) from 9 different cell lines by using anti-CD4 monoclonal...
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01730
Other Accession 920
Reactivity Human, Monkey
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Clone Names 5D9
Calculated MW 51111 Da
Dilution IHC-P (10 µg/ml), WB (1:2000),
Additional Information
Gene ID 920
Other Names CD4, CD4 antigen, CD4 receptor, CD4mut, CD4 antigen (p55), CD4 molecule
Target/Specificity Human CD4
Reconstitution & Storage PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing.
PrecautionsCD4 Antibody (clone 5D9) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD4
Function Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
Cellular Location Cell membrane; Single-pass type I membrane protein Note=Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum
Research Areas
Citations (0)

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Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.


Maddon P.J.,et al.Cell 42:93-104(1985).
Littman D.R.,et al.Cell 55:541-541(1988).
Ansari-Lari M.A.,et al.Genome Res. 6:314-326(1996).
Ansari-Lari M.A.,et al.Genome Res. 7:268-280(1997).
Hodge T.W.,et al.Hum. Immunol. 30:99-104(1991).

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$ 395.00
Cat# ALS16661
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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