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NME2 Antibody (aa91-140)

Rabbit Polyclonal Antibody

  • IHC - NME2 Antibody (aa91-140) ALS16689
    Anti-NME2 / NM23 antibody IHC staining of human spleen.
  • WB - NME2 Antibody (aa91-140) ALS16689
    Western blot of extracts from K562 cells, using NM23 Antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P22392
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 17298 Da
Dilution ELISA (1:1000), IHC-P (10 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 4831;654364
Other Names Nucleoside diphosphate kinase B, NDK B, NDP kinase B,, C-myc purine-binding transcription factor PUF, Histidine protein kinase NDKB,, nm23-H2, NME2, NM23B
Target/Specificity NM23 Antibody detects endogenous levels of total NM23 protein.
Reconstitution & Storage PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.
PrecautionsNME2 Antibody (aa91-140) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NME2
Synonyms NM23B
Function Major role in the synthesis of nucleoside triphosphates other than ATP. Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically (PubMed:8392752). Exhibits histidine protein kinase activity.
Cellular Location Cytoplasm. Nucleus. Cell projection, lamellipodium. Cell projection, ruffle. Note=Isoform 2 is mainly cytoplasmic and isoform 1 and isoform 2 are excluded from the nucleolus. Colocalizes with ITGB1 and ITGB1BP1 at the edge or peripheral ruffles and lamellipodia during the early stages of cell spreading on fibronectin or collagen but not on vitronectin or laminin substrates
Tissue Location Ubiquitously expressed.
Volume 50 µl
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$ 395.00
Cat# ALS16689
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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