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DOK6 Antibody (aa111-160)

Rabbit Polyclonal Antibody

     
  • IHC - DOK6 Antibody (aa111-160) ALS16711
    Anti-DOK6 antibody IHC staining of human brain, cortex.
    detail
  • IF - DOK6 Antibody (aa111-160) ALS16711
    Immunofluorescence of A549 cells, using DOK6 Antibody.
    detail
  • WB - DOK6 Antibody (aa111-160) ALS16711
    Western blot of extracts from COLO cells, using DOK6 Antibody.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q6PKX4
Other Accession 220164
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 38318 Da
Dilution ELISA (1:10000), IF (1:100 - 1:500), IHC-P (10 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 220164
Other Names DOK6, DOK5L, Docking protein 5-like, Docking protein 6, HsT3226
Target/Specificity DOK6 Antibody detects endogenous levels of total DOK6 protein.
Reconstitution & Storage PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.
PrecautionsDOK6 Antibody (aa111-160) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DOK6
Synonyms DOK5L
Function DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance.
Tissue Location Highly expressed in fetal and adult brain. Highly expressed in the cerebellum. Weak expression in kidney, spinal cord and testis.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret- mediated neurite growth. May have a role in brain development and/or maintenance.

References

Crowder R.J.,et al.J. Biol. Chem. 279:42072-42081(2004).
Nusbaum C.,et al.Nature 437:551-555(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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Discontinued
Cat# ALS16711
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