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>   home   >   Products   >   Primary Antibodies   >   NARG1 / NAA15 Antibody (aa221-270)   

NARG1 / NAA15 Antibody (aa221-270)

Rabbit Polyclonal Antibody

     
  • IHC - NARG1 / NAA15 Antibody (aa221-270) ALS16721
    Anti-NARG1 / NAA15 antibody IHC staining of human brain, cortex.
  • WB - NARG1 / NAA15 Antibody (aa221-270) ALS16721
    Western blot of extracts from HUVEC cells, using NARG1 Antibody.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9BXJ9
Other Accession 80155
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 101272 Da
Dilution ELISA (1:20000), IHC-P (10 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 80155
Other Names NAA15, Ga19, Gastric cancer antigen Ga19, Protein tubedown-1, Tubedown-1, NARG1, TBDN100, N-terminal acetyltransferase, NATH, NMDA receptor regulated 1
Target/Specificity NARG1 Antibody detects endogenous levels of total NARG1 protein.
Reconstitution & Storage PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year.
PrecautionsNARG1 / NAA15 Antibody (aa221-270) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NAA15
Synonyms GA19, NARG1, NATH, TBDN100
Function Auxillary subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. The NAT activity may be important for vascular, hematopoietic and neuronal growth and development. Required to control retinal neovascularization in adult ocular endothelial cells. In complex with XRCC6 and XRCC5 (Ku80), up-regulates transcription from the osteocalcin promoter.
Cellular Location Cytoplasm. Nucleus. Note=Mainly cytoplasmic, nuclear in some cases. Present in the free cytosolic and cytoskeleton-bound polysomes, but not in the membrane-bound polysomes
Tissue Location Expressed at high levels in testis and in ocular endothelial cells. Also found in brain (corpus callosum), heart, colon, bone marrow and at lower levels in most adult tissues, including thyroid, liver, pancreas, mammary and salivary glands, lung, ovary, urogenital system and upper gastrointestinal tract. Overexpressed in gastric cancer, in papillary thyroid carcinomas and in a Burkitt lymphoma cell line (Daudi) Specifically suppressed in abnormal proliferating blood vessels in eyes of patients with proliferative diabetic retinopathy
Volume 50 µl
Citations (0)

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Background

Auxillary subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. The NAT activity may be important for vascular, hematopoietic and neuronal growth and development. Required to control retinal neovascularization in adult ocular endothelial cells. In complex with XRCC6 and XRCC5 (Ku80), up-regulates transcription from the osteocalcin promoter.

References

Line A.,et al.Br. J. Cancer 86:1824-1830(2002).
Willis D.M.,et al.J. Biol. Chem. 277:37280-37291(2002).
Fluge O.,et al.Oncogene 21:5056-5068(2002).
He Y.G.,et al.Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao 34:353-357(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS16721
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