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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   CD59 Antibody (N-Terminus)   

CD59 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - CD59 Antibody (N-Terminus) ALS16747
    Anti-CD59 antibody IHC staining of human placenta.
  • IHC - CD59 Antibody (N-Terminus) ALS16747
    Anti-CD59 antibody IHC staining of human kidney.
  • WB - CD59 Antibody (N-Terminus) ALS16747
    Western blot analysis of CD59 in mouse spleen tissue lysate with CD59 antibody at 1 ug/ml
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P13987
Other Accession 966
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 14177 Da
Dilution IHC-P (10 µg/ml), WB (1 - 2 µg/ml),
Additional Information
Gene ID 966
Other Names CD59, 16.3A5, 1F5, 1F5 antigen, CD59 glycoprotein, EL32, EJ16, G344, HRF-20, MAC-IP, MACIF, Ly-6-like protein, MEM43, MIRL, MEM43 antigen, MIN2, MIN3, MSK21, p18-20, Protectin, MAC-inhibitory protein, MIC11, T cell-activating protein, CD59 antigen, E ...
Target/Specificity Human CD59
Reconstitution & Storage PBS, 0.02% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsCD59 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD59
Synonyms MIC11, MIN1, MIN2, MIN3, MSK21
Function Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Soluble form found in a number of tissues
Research Areas
Citations (0)

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Background

Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

References

Davies A.,et al.J. Exp. Med. 170:637-654(1989).
Philbrick W.M.,et al.Eur. J. Immunol. 20:87-92(1990).
Okada H.,et al.Biochem. Biophys. Res. Commun. 162:1553-1559(1989).
Sugita Y.,et al.J. Biochem. 106:555-557(1989).
Sawada R.,et al.DNA Cell Biol. 9:213-220(1990).

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$ 395.00
Cat# ALS16747
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