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MTERF3 / MTERFD1 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - MTERF3 / MTERFD1 Antibody (C-Terminus) ALS16753
    Anti-MTERFD1 antibody IHC staining of human lung.
    detail
  • WB - MTERF3 / MTERFD1 Antibody (C-Terminus) ALS16753
    Western blot analysis of MTERFD1 in 3T3 cell lysate with MTERFD1 antibody at (A) 1 and (B) 2 ug/ml.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q96E29
Other Accession 51001
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 47971 Da
Dilution IHC-P (10 µg/ml), WB (1 - 2 µg/ml),
Additional Information
Gene ID 51001
Other Names MTERF3, CGI-12, MTERF domain containing 1, MTERFD1
Target/Specificity At least three isoforms of MTERFD1 are known to exist. MTERFD1 antibody is predicted to not cross-react with other MTERFD protein family members.
Reconstitution & Storage PBS, 0.02% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsMTERF3 / MTERFD1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MTERF3
Synonyms MTERFD1
Function Binds promoter DNA and regulates initiation of transcription (PubMed:17662942). Required for normal mitochondrial transcription and translation, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function (By similarity). Maintains 16S rRNA levels and functions in mitochondrial ribosome assembly by regulating the biogenesis of the 39S ribosomal subunit (By similarity).
Cellular Location Mitochondrion
Tissue Location Highly expressed in heart, liver, kidney and testis. Detected at lower levels in brain, spleen and lung
Citations (0)
citation

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Background

Binds promoter DNA and regulates initiation of transcription. Required for normal mitochondrial transcription, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function (By similarity).

References

Lai C.-H.,et al.Genome Res. 10:703-713(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Nusbaum C.,et al.Nature 439:331-335(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Park C.B.,et al.Cell 130:273-285(2007).

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Discontinued
Cat# ALS16753
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