|Application ||WB, IHC-P, E|
|Calculated MW||47971 Da|
|Dilution||IHC-P (10 µg/ml), WB (1 - 2 µg/ml),|
|Other Names||MTERF3, CGI-12, MTERF domain containing 1, MTERFD1|
|Target/Specificity||At least three isoforms of MTERFD1 are known to exist. MTERFD1 antibody is predicted to not cross-react with other MTERFD protein family members.|
|Reconstitution & Storage||PBS, 0.02% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||MTERF3 / MTERFD1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds promoter DNA and regulates initiation of transcription. Required for normal mitochondrial transcription, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function (By similarity).|
|Tissue Location||Highly expressed in heart, liver, kidney and testis. Detected at lower levels in brain, spleen and lung|
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Provided below are standard protocols that you may find useful for product applications.
Binds promoter DNA and regulates initiation of transcription. Required for normal mitochondrial transcription, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function (By similarity).
Lai C.-H.,et al.Genome Res. 10:703-713(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Nusbaum C.,et al.Nature 439:331-335(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Park C.B.,et al.Cell 130:273-285(2007).
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