TLX2 / NCX Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
---|---|
Primary Accession | O43763 |
Other Accession | 3196 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 30251 Da |
Dilution | IF (20 µg/ml), IHC-P (10 µg/ml), WB (0.5 - 1 µg/ml), |
Gene ID | 3196 |
---|---|
Other Names | TLX2, Enx, Homeobox protein Hox-11L1, Neural crest homeobox protein, Homeo box 11-like 1, T-cell leukemia homeobox 2, NCX, HOX11L1, T-cell leukemia, homeobox 2 |
Target/Specificity | TLX2 antibody is predicted to not cross-react with other TLX proteins. |
Reconstitution & Storage | PBS, 0.02% sodium azide. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
Precautions | TLX2 / NCX Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TLX2 |
---|---|
Synonyms | HOX11L1, NCX |
Function | Transcription activator that binds DNA elements with the consensus sequence 5'-CGGTAATTGG-3'. Binds DNA via its homeobox. Required for normal cell death of enteric neurons in the gastrointestinal tract. Required for normal development of the enteric nervous system, and for proper development of normal motility of the gastrointestinal tract (By similarity). |
Cellular Location | Nucleus. |
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Background
Transcription activator that binds DNA elements with the consensus sequence 5'-CGGTAATTGG-3'. Binds DNA via its homeobox. Required for normal cell death of enteric neurons in the gastrointestinal tract. Required for normal development of the enteric nervous system, and for proper development of normal motility of the gastrointestinal tract (By similarity).
References
Iitsuka Y.,et al.J. Biol. Chem. 274:24401-24407(1999).
Delgado P.,et al.Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Moretti P.,et al.Gene 144:213-219(1994).
Miyazono K.,et al.EMBO J. 29:1613-1623(2010).
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