|Application ||WB, IHC, IHC-P, IF|
|Calculated MW||55391 Da|
|Dilution||IF (1:500), IHC (1:5000), IHC-P (1:50), WB (1:10000),|
|Other Names||INA, 66 kDa neurofilament protein, Alpha Internexin, Alpha-internexin, Alpha-Inx, NEF5, Neurofilament 5, Neurofilament-66, NF-66, TXBP-1, Neurofilament 5 (66kD)|
|Target/Specificity||Clone 2E3 reacts with human alpha-internexin and with this protein in all mammalian species tested to date.|
|Reconstitution & Storage||Tissue culture supernatant. +4°C or -20°C, Avoid repeated freezing and thawing.|
|Precautions||INA / Alpha Internexin Antibody (clone 2E3) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.|
|Tissue Location||Found predominantly in adult CNS.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.
Chan S.-O.,et al.Brain Res. Mol. Brain Res. 29:177-184(1995).
Deloukas P.,et al.Nature 429:375-381(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
Matsuoka S.,et al.Science 316:1160-1166(2007).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.