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INA / Alpha Internexin Antibody (clone 2E3)

Mouse Monoclonal Antibody

     
  • IHC - INA / Alpha Internexin Antibody (clone 2E3) ALS16820
    Anti-INA / Alpha Internexin antibody IHC staining of human brain, cerebellum.
  • IHC - INA / Alpha Internexin Antibody (clone 2E3) ALS16820
    Rat facial nucleus before (left) and after (right) facial nerve lesion.
  • WB - INA / Alpha Internexin Antibody (clone 2E3) ALS16820
    Blot of homogenate of rat facial nucleus incubated with INA / Alpha Internexin antibody, which...
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IHC-P, IF
Primary Accession Q16352
Other Accession 9118
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 2E3
Calculated MW 55391 Da
Dilution IF (1:500), IHC (1:5000), IHC-P (1:50), WB (1:10000),
Additional Information
Gene ID 9118
Other Names INA, 66 kDa neurofilament protein, Alpha Internexin, Alpha-internexin, Alpha-Inx, NEF5, Neurofilament 5, Neurofilament-66, NF-66, TXBP-1, Neurofilament 5 (66kD)
Target/Specificity Clone 2E3 reacts with human alpha-internexin and with this protein in all mammalian species tested to date.
Reconstitution & Storage Tissue culture supernatant. +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsINA / Alpha Internexin Antibody (clone 2E3) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name INA
Synonyms NEF5
Function Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.
Tissue Location Found predominantly in adult CNS.
Volume 50 µl
Research Areas
Citations (0)

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Background

Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges.

References

Chan S.-O.,et al.Brain Res. Mol. Brain Res. 29:177-184(1995).
Deloukas P.,et al.Nature 429:375-381(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
Matsuoka S.,et al.Science 316:1160-1166(2007).

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$ 395.00
Cat# ALS16820
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