|Application ||WB, IHC-P, IF|
|Reactivity||Human, Mouse, Rat, Pig, Bovine|
|Calculated MW||45120 Da|
|Dilution||IF (1:1000), IHC-P (1:100), WB (1:5000),|
|Other Names||SAG, 48 kDa protein, Arrestin 1, ARRESTIN, S-arrestin, S-AG, Retinal S-antigen, Rod photoreceptor arrestin, S-antigen, RP47|
|Target/Specificity||Clone S128 is known to react with visual arrestin from human, bovine, mouse, pig and rat.|
|Reconstitution & Storage||PBS, 10 mM sodium azide. +4°C or -20°C, Avoid repeated freezing and thawing.|
|Precautions||SAG / Arrestin Antibody (clone S128) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated- phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase.|
|Tissue Location||Retina and pineal gland.|
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Provided below are standard protocols that you may find useful for product applications.
Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated- phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase.
Yamaki K.,et al.FEBS Lett. 234:39-43(1988).
Yamaki K.,et al.FEBS Lett. 236:507-507(1988).
Yamamoto S.,et al.Nat. Genet. 15:175-178(1997).
Hillier L.W.,et al.Nature 434:724-731(2005).
Roni V.,et al.BMC Genomics 8:42-42(2007).
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