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TDO2 Antibody (clone 4G2)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | P48775 |
| Other Accession | 6999 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Clone Names | 4G2 |
| Calculated MW | 47872 Da |
| Dilution | IHC-P (10 µg/ml), WB (1:2000), |
| Gene ID | 6999 |
|---|---|
| Other Names | TDO2, TDO, TO, TRPO, Tryptophan pyrrolase, Tryptophan oxygenase, Tryptophan 2, 3-dioxygenase, Tryptophanase, Tryptamin 2, 3-dioxygenase |
| Target/Specificity | Human TDO / TDO2 |
| Reconstitution & Storage | PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing. |
| Precautions | TDO2 Antibody (clone 4G2) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TDO2 {ECO:0000255|HAMAP-Rule:MF_03020} |
|---|---|
| Synonyms | TDO |
| Function | Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin (By similarity).
References
Comings D.E.,et al.Genomics 29:390-396(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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