|Application ||WB, IHC-P|
|Calculated MW||47872 Da|
|Dilution||IHC-P (10 µg/ml), WB (1:2000),|
|Other Names||TDO2, TDO, TO, TRPO, Tryptophan pyrrolase, Tryptophan oxygenase, Tryptophan 2, 3-dioxygenase, Tryptophanase, Tryptamin 2, 3-dioxygenase|
|Target/Specificity||Human TDO / TDO2|
|Reconstitution & Storage||PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing.|
|Precautions||TDO2 Antibody (clone 4G2) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin (By similarity).|
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Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin (By similarity).
Comings D.E.,et al.Genomics 29:390-396(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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