|Application ||WB, IHC-P, E|
|Calculated MW||54848 Da|
|Dilution||ELISA (1:20000 - 1:80000), IHC-P (5 µg/ml), WB (1:1000 - 1:2000),|
|Other Names||ALDH3A2, Aldehyde dehydrogenase 10, ALDH10, Fatty aldehyde dehydrogenase, FALDH, SLS|
|Reconstitution & Storage||PBS, pH 7.4, 0.02% sodium azide. Store at -20°C for up to one year.|
|Precautions||ALDH3A2 Antibody (aa166-400) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side|
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Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid.
de Laurenzi V.,et al.Nat. Genet. 12:52-57(1996).
Rogers G.R.,et al.Genomics 39:127-135(1997).
Chang C.,et al.Genomics 40:80-85(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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