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ALDH3A2 Antibody (aa166-400)

Rabbit Polyclonal Antibody

     
  • IHC - ALDH3A2 Antibody (aa166-400) ALS16835
    Anti-ALDH3A2 antibody IHC staining of human liver.
    detail
  • IHC - ALDH3A2 Antibody (aa166-400) ALS16835
    Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
    detail
  • WB - ALDH3A2 Antibody (aa166-400) ALS16835
    western blot analysis of 293t,a-549 cell and fetal testis lysate wirh anti-aldh3a2 antibody
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P51648
Other Accession 224
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 54848 Da
Dilution ELISA (1:20000 - 1:80000), IHC-P (5 µg/ml), WB (1:1000 - 1:2000),
Additional Information
Gene ID 224
Other Names ALDH3A2, Aldehyde dehydrogenase 10, ALDH10, Fatty aldehyde dehydrogenase, FALDH, SLS
Target/Specificity Human ALDH3A2.
Reconstitution & Storage PBS, pH 7.4, 0.02% sodium azide. Store at -20°C for up to one year.
PrecautionsALDH3A2 Antibody (aa166-400) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ALDH3A2
Function Catalyzes the oxidation of medium and long chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length (PubMed:9133646, PubMed:22633490, PubMed:25047030, PubMed:18035827, PubMed:9662422, PubMed:18182499). Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid (PubMed:22633490).
Cellular Location Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side {ECO:0000250|UniProtKB:P30839}
Tissue Location Detected in liver (at protein level).
Research Areas
Citations (0)
citation

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Background

Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid.

References

de Laurenzi V.,et al.Nat. Genet. 12:52-57(1996).
Rogers G.R.,et al.Genomics 39:127-135(1997).
Chang C.,et al.Genomics 40:80-85(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

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Discontinued
Cat# ALS16835
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