|Application ||WB, IHC-P|
|Calculated MW||96386 Da|
|Dilution||IHC-P (7.5 µg/ml), WB (1:500 - 1:3000),|
|Other Names||ATP6V0A4, ATP6N1B, Renal tubular acidosis, RTA1C, STV1, V-ATPase 116 kDa, V-ATPase alpha 4, RTADR, ATP6N2, RDRTA2, V-ATPase 116 kDa isoform a4, VPH1, VPP2|
|Reconstitution & Storage||0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal. Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.|
|Precautions||ATP6V0A4 Antibody (aa53-295) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Part of the proton channel of the V-ATPase that is involved in normal vectorial acid transport into the urine by the kidney.|
|Cellular Location||Apical cell membrane; Multi-pass membrane protein. Note=Present at high density almost exclusively on the apical surface of alpha-intercalated cells in the cortical collecting ducts of the distal nephron|
|Tissue Location||Expressed in adult and fetal kidney. Found in the inner ear.|
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Provided below are standard protocols that you may find useful for product applications.
Part of the proton channel of the V-ATPase that is involved in normal vectorial acid transport into the urine by the kidney.
Smith A.N.,et al.Nat. Genet. 26:71-75(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
Scherer S.W.,et al.Science 300:767-772(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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