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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   PDGF-BB Antibody (aa21-70)   

PDGF-BB Antibody (aa21-70)

Rabbit Polyclonal Antibody

     
  • IHC - PDGF-BB Antibody (aa21-70) ALS16929
    Anti-PDGF-BB antibody IHC staining of human skeletal muscle.
  • WB - PDGF-BB Antibody (aa21-70) ALS16929
    Western blot analysis of PDGFB pAb at 1:500.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P01127
Other Accession 5155
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 27283 Da
Dilution IHC-P (10 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 5155
Other Names PDGFB, Becaplermin, PDGF-BB, PDGF-b, SSV, PDGF subunit B, PDGF-2, PDGF2, Proto-oncogene c-Sis, SIS, C-sis, PDGF, B chain
Target/Specificity Human PDGF-BB / PDGFB
Reconstitution & Storage PBS, pH 7.2, 0.05% sodium azide. Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PrecautionsPDGF-BB Antibody (aa21-70) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDGFB
Synonyms PDGF2, SIS
Function Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin (PubMed:26599395). Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).
Cellular Location Secreted. Note=Released by platelets upon wounding
Tissue Location Expressed at high levels in the heart, brain (sustantia nigra), placenta and fetal kidney. Expressed at moderate levels in the brain (hippocampus), skeletal muscle, kidney and lung.
Volume 50 µl
Research Areas
Citations (0)

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Background

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).

References

Josephs S.F.,et al.Science 225:636-639(1984).
Collins T.,et al.Nature 316:748-750(1985).
Ratner L.,et al.Nucleic Acids Res. 13:5007-5018(1985).
Rao C.D.,et al.Cold Spring Harb. Symp. Quant. Biol. 51:959-966(1986).
Rao C.D.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:2392-2396(1986).

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$ 395.00
Cat# ALS16929
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