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LRCH4 Antibody (clone 1F8)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | O75427 |
| Other Accession | 4034 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Clone Names | 1F8 |
| Calculated MW | 73450 Da |
| Dilution | IHC-P (10 µg/ml), WB (1:2000), |
| Gene ID | 4034 |
|---|---|
| Other Names | LRCH4, Leucine-rich neuronal protein, Leucine rich repeat neuronal 4, PP14183, LRN |
| Target/Specificity | Human LRCH4 |
| Reconstitution & Storage | PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing. |
| Precautions | LRCH4 Antibody (clone 1F8) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LRCH4 (HGNC:6691) |
|---|---|
| Synonyms | LRN, LRRN1, LRRN4 |
| Function | Accessory protein that regulates signaling by multiple TLRs, acting as a broad-spanning regulator of the innate immune response. In macrophages, binds LPS and promotes proper docking of LPS in lipid raft membrane. May be required for lipid raft maintenance. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q921G6}; Single-pass membrane protein |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Gloeckner G.,et al.Genome Res. 8:1060-1073(1998).
Scherer S.W.,et al.Science 300:767-772(2003).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
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