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APOB / Apolipoprotein B Antibody (clone GF1)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, E |
|---|---|
| Primary Accession | P04114 |
| Other Accession | 338 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Clone Names | GF1 |
| Calculated MW | 515545 Da |
| Dilution | IHC-P (10 µg/ml), |
| Gene ID | 338 |
|---|---|
| Other Names | APOB, ApoB-100, Apolipoprotein B-48, ApoB-48, Apolipoprotein B, FLDB, LDLCQ4, Mutant Apo B 100, Apo B-100, Apolipoprotein B-100, Apolipoprotein B48 |
| Target/Specificity | Apo B: 100%, Apo A-I: 0%, Apo A-II: 0%. |
| Reconstitution & Storage | PBS, pH 7.5, 0.05% sodium azide. May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. |
| Precautions | APOB / Apolipoprotein B Antibody (clone GF1) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | APOB |
|---|---|
| Function | Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. |
| Cellular Location | Cytoplasm. Secreted. Lipid droplet |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
References
Knott T.C.,et al.Nucleic Acids Res. 14:7501-7503(1986).
Ludwig E.H.,et al.DNA 6:363-372(1987).
Chen S.-H.,et al.J. Biol. Chem. 261:12918-12921(1986).
Law S.W.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:8142-8146(1986).
Cladaras C.,et al.EMBO J. 5:3495-3507(1986).
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