|Application ||IHC-P, E|
|Calculated MW||515605 Da|
|Dilution||IHC-P (10 µg/ml),|
|Other Names||APOB, ApoB-100, Apolipoprotein B-48, ApoB-48, Apolipoprotein B, FLDB, LDLCQ4, Mutant Apo B 100, Apo B-100, Apolipoprotein B-100, Apolipoprotein B48|
|Target/Specificity||Apo B: 100%, Apo A-I: 0%, Apo A-II: 0%.|
|Reconstitution & Storage||PBS, pH 7.5, 0.05% sodium azide. May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months.|
|Precautions||APOB / Apolipoprotein B Antibody (clone GF1) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.|
|Cellular Location||Cytoplasm. Secreted|
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Provided below are standard protocols that you may find useful for product applications.
Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
Knott T.C.,et al.Nucleic Acids Res. 14:7501-7503(1986).
Ludwig E.H.,et al.DNA 6:363-372(1987).
Chen S.-H.,et al.J. Biol. Chem. 261:12918-12921(1986).
Law S.W.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:8142-8146(1986).
Cladaras C.,et al.EMBO J. 5:3495-3507(1986).
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