|Application ||IHC-P, E|
|Calculated MW||10085 Da|
|Dilution||ELISA (1:10000), IHC-P (20 µg/ml),|
|Other Names||CCL3, C-C motif chemokine 3, G0S19-1, Mip1alpha, SCYA3, SIS-beta, Chemokine (C-C motif) ligand 3, LD78ALPHA, MIP-1-alpha, MIP1A, PAT 464.1, Small-inducible cytokine A3|
|Target/Specificity||MIP-1 alpha antibody detects endogenous levels of MIP-1 alpha .|
|Reconstitution & Storage||PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C.|
|Precautions||CCL3 / MIP-1-Alpha Antibody (aa26-75) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||G0S19-1, MIP1A, SCYA3|
|Function||Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).|
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Provided below are standard protocols that you may find useful for product applications.
Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
Obaru K.,et al.J. Biochem. 99:885-894(1986).
Zipfel P.F.,et al.J. Immunol. 142:1582-1590(1989).
Blum S.,et al.DNA Cell Biol. 9:589-602(1990).
Nakao M.,et al.Mol. Cell. Biol. 10:3646-3658(1990).
Jang J.S.,et al.Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.
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