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KRT5 / CK5 / Cytokeratin 5 Antibody (Synthetic peptide, corresponding to amino acids 550-600 of
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF |
|---|---|
| Primary Accession | P13647 |
| Other Accession | 3852 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 62378 Da |
| Dilution | IF (1:50 - 1:200), IHC-P (2.5 µg/ml), WB (1:500 - 1:1000), |
| Gene ID | 3852 |
|---|---|
| Other Names | KRT5, 58 kd cytokeratin, 58 kDa cytokeratin, CK5, CK-5, Cytokeratin-5, DDD, EBS2, Keratin 5, KRT5A, Type-II keratin Kb5, Cytokeratin 5, K5, Keratin-5 |
| Target/Specificity | Human Cytokeratin 5 / Keratin 5 |
| Reconstitution & Storage | PBS, pH 7.2, 0.05% sodium azide. Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Precautions | KRT5 / CK5 / Cytokeratin 5 Antibody (Synthetic peptide, corresponding to amino acids 550-600 of is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KRT5 |
|---|---|
| Function | Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress (By similarity). Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes (By similarity). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Expressed in corneal epithelium (at protein level) (PubMed:26758872). Expressed in keratinocytes (at protein level) (PubMed:20128788, PubMed:31302245). |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Eckert R.L.,et al.DNA 7:337-345(1988).
Lersch R.,et al.Mol. Cell. Biol. 9:3685-3697(1989).
Whittock N.V.,et al.Biochem. Biophys. Res. Commun. 274:149-152(2000).
Lersch R.,et al.Mol. Cell. Biol. 8:486-493(1988).
Xu Z.,et al.Clin. Exp. Dermatol. 29:74-76(2004).
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