|Application ||WB, IHC-P, IF|
|Calculated MW||88844 Da|
|Dilution||IF (1:100 - 1:1000), IHC-P (5 µg/ml), WB (1:500 - 1:3000),|
|Other Names||CSRP2BP, ATAC2, CSRP2 binding protein, DJ717M23.1, CRP2 binding partner, CRP2BP, CSRP2-binding protein, PRO1194, ATAC component 2 homolog, CRP2 binding protein, CRP2-binding partner, KAT14|
|Reconstitution & Storage||PBS, pH 7, 1% BSA, 20% Glycerol, 0.01% Thimerosal. Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.|
|Precautions||CSRP2BP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle.|
|Cellular Location||Nucleus. Cytoplasm. Note=Mainly nuclear.|
|Tissue Location||Expressed in skeletal muscle, heart, lung, placenta, brain, liver, pancreas and kidney. High expression in skeletal muscle and heart. Lower expression in lung|
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Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 414:865-871(2001).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Weiskirchen R.,et al.Biochem. Biophys. Res. Commun. 274:655-663(2000).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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