HAK / ALPK2 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q86TB3 |
Other Accession | 115701 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 237013 Da |
Dilution | ELISA (1:10000 - 1:40000), IHC-P (5 µg/ml), WB (1:500 - 1:1000), |
Gene ID | 115701 |
---|---|
Other Names | ALPK2, Alpha-protein kinase 2, HAK, Heart alpha-protein kinase, Alpha-kinase 2, Heart alpha-kinase |
Target/Specificity | Human HAK / ALPK2. |
Reconstitution & Storage | PBS, pH 7.4, 0.02% sodium azide. Store at -20°C for up to one year. |
Precautions | HAK / ALPK2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ALPK2 |
---|---|
Synonyms | HAK |
Function | Protein kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation (PubMed:10021370). Regulates cardiac development and cardiomyocyte differentiation by negatively regulating Wnt/beta-catenin signaling (PubMed:29888752). |
Cellular Location | Basolateral cell membrane |
Tissue Location | Expressed in developing cardiac tissue and cardiomyocytes (at protein level). |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation.
References
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Nusbaum C.,et al.Nature 437:551-555(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ryazanov A.G.,et al.Curr. Biol. 9:R43-R45(1999).
Greenman C.,et al.Nature 446:153-158(2007).
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