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HAK / ALPK2 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - HAK / ALPK2 Antibody (C-Terminus) ALS17044
    Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
    detail
  • WB - HAK / ALPK2 Antibody (C-Terminus) ALS17044
    Western Blot analysis of fetal liver lysate with anti-ALPK2 antibody
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q86TB3
Other Accession 115701
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 237013 Da
Dilution ELISA (1:10000 - 1:40000), IHC-P (5 µg/ml), WB (1:500 - 1:1000),
Additional Information
Gene ID 115701
Other Names ALPK2, Alpha-protein kinase 2, HAK, Heart alpha-protein kinase, Alpha-kinase 2, Heart alpha-kinase
Target/Specificity Human HAK / ALPK2.
Reconstitution & Storage PBS, pH 7.4, 0.02% sodium azide. Store at -20°C for up to one year.
PrecautionsHAK / ALPK2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ALPK2
Synonyms HAK
Function Protein kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation (PubMed:10021370). Regulates cardiac development and cardiomyocyte differentiation by negatively regulating Wnt/beta-catenin signaling (PubMed:29888752).
Cellular Location Basolateral cell membrane
Tissue Location Expressed in developing cardiac tissue and cardiomyocytes (at protein level).
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation.

References

Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Nusbaum C.,et al.Nature 437:551-555(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ryazanov A.G.,et al.Curr. Biol. 9:R43-R45(1999).
Greenman C.,et al.Nature 446:153-158(2007).

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$ 467.50
Cat# ALS17044
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