|Application ||WB, IHC-P, E|
|Calculated MW||36461 Da|
|Dilution||ELISA (1:10000), IHC-P (5 µg/ml), WB (1:500 - 1:1000),|
|Other Names||MRGPRX4, MRGX4, SNSR6, SNSR5, MAS-related GPR, member X4|
|Target/Specificity||MRGX4 Antibodyantibody detects endogenous levels of MRGX4.|
|Reconstitution & Storage||PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C.|
|Precautions||MRGPRX4 / MRGX4 Antibody (aa258-307) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||MRGX4, SNSR5, SNSR6|
|Function||Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons|
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Provided below are standard protocols that you may find useful for product applications.
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity).
Dong X.,et al.Cell 106:619-632(2001).
Lembo P.M.C.,et al.Nat. Neurosci. 5:201-209(2002).
Taylor T.D.,et al.Nature 440:497-500(2006).
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