|Application ||WB, IHC-P, Flo|
|Calculated MW||44002 Da|
|Dilution||Flo (1:100), IHC-P (5 µg/ml), WB (1:2000),|
|Other Names||SERPINE2, GDNPF, GDN, PNI, PN1, Protease nexin I, Nexin, Protease nexin 1, Serpin E2, Glia-derived nexin, Peptidase inhibitor 7, PI-7, PI7, PN-1|
|Reconstitution & Storage||PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide. Store at -20°C. Minimize freezing and thawing.|
|Precautions||SERPINE2 / Nexin Antibody (clone 2C9) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.|
|Cellular Location||Secreted, extracellular space.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.
Sommer J.,et al.Biochemistry 26:6407-6410(1987).
Gloor S.M.,et al.Cell 47:687-693(1986).
McGrogan M.,et al.Biotechnology (N.Y.) 6:172-177(1988).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
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