|Application ||WB, IHC-P, E|
|Calculated MW||69195 Da|
|Dilution||IHC-P (10 µg/ml),|
|Other Names||PCK1, PEPCKC, Phosphopyruvate carboxylase, PEP carboxykinase, PEPCK-C, PEPCK1|
|Reconstitution & Storage||PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PCK1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|
|Tissue Location||Major sites of expression are liver, kidney and adipocytes|
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
Stoffel M.,et al.Hum. Mol. Genet. 2:1-4(1993).
Ting C.-N.,et al.Genomics 16:698-706(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 414:865-871(2001).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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