|Application ||WB, IHC-P, IF|
|Reactivity||Human, Mouse, Rat, Monkey, Dog|
|Calculated MW||24608 Da|
|Dilution||IF (1:50 - 1:250), IHC-P (5 µg/ml), WB (1:250 - 1:2000),|
|Other Names||RAB27B, C25KG, Ras-related protein Rab-27B|
|Target/Specificity||Detects Rab27b by Western blot in the following human, rat and mouse whole cell lysates and transfected cells with GFP-Rab27b. This antibody is specific for Rab27b. It does not recognise Rab27a protein.|
|Reconstitution & Storage||PBS, 20% glycerol, 0.05% sodium azide. Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.|
|Precautions||RAB27B Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in targeting uroplakins to urothelial apical membranes.|
|Cellular Location||Membrane; Lipid-anchor.|
|Tissue Location||Expressed primarily in testis.|
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Provided below are standard protocols that you may find useful for product applications.
May be involved in targeting uroplakins to urothelial apical membranes.
Chen D.,et al.Biochem. Mol. Med. 60:27-37(1997).
Chen D.,et al.Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases.
Ramalho J.S.,et al.BMC Genet. 2:2-2(2001).
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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