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>   home   >   Products   >   Primary Antibodies   >   WIPI2 Antibody (C-Terminus, clone 2A2)   

WIPI2 Antibody (C-Terminus, clone 2A2)

Mouse Monoclonal Antibody

  • IHC-P - WIPI2 Antibody (C-Terminus, clone 2A2) ALS17227
    Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • IHC-P - WIPI2 Antibody (C-Terminus, clone 2A2) ALS17227
    Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y4P8
Other Accession 26100
Reactivity Human, Mouse, Rat, Hamster, Guinea Pig
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 2A2
Calculated MW 49408 Da
Dilution IHC-P (10 µg/ml),
Additional Information
Gene ID 26100
Other Names WIPI2, ATG18B, Atg21, DKFZP434J154, WIPI-2, WIPI49-like protein 2, CGI-50
Target/Specificity Recognizes WIPI2, a mammalian ortholog of Atg18. WIPI2 is recruited to early autophagosomal structures and is required for their maturation into mature autophagosomes.
Reconstitution & Storage PBS, 0.09% sodium azide. +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsWIPI2 Antibody (C-Terminus, clone 2A2) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WIPI2
Function Early component of the autophagy machinery being involved in formation of preautophagosomal structures and their maturation into mature phagosomes in response to phosphatidylinositol 3-phosphate (PtdIns3P). May bind PtdIns3P.
Cellular Location Preautophagosomal structure membrane; Peripheral membrane protein; Cytoplasmic side Note=Localizes to omegasomes membranes which are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures. Enriched at preautophagosomal structure membranes in response to PtdIns3P.
Tissue Location Ubiquitously expressed (at protein level). Highly expressed in heart, skeletal muscle and pancreas Expression is down-regulated in pancreatic and in kidney tumors
Citations (0)

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Early component of the autophagy machinery being involved in formation of preautophagosomal structures and their maturation into mature phagosomes in response to phosphatidylinositol 3-phosphate (PtdIns3P). May bind PtdIns3P.


Proikas-Cezanne T.,et al.Oncogene 23:9314-9325(2004).
Lai C.-H.,et al.Genome Res. 10:703-713(2000).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS17227
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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