|Application ||WB, IHC-P, E|
|Predicted||Human, Mouse, Rat|
|Calculated MW||50854 Da|
|Dilution||ELISA, IHC-P (10 µg/ml), WB (1 - 2 µg/ml)|
|Other Names||LANCL2, G protein-coupled receptor 69B, GPR69B, LanC-like protein 2, Tasp|
|Target/Specificity||LANCL2 antibody is human, mouse and rat reactive.|
|Reconstitution & Storage||PBS, 0.02% sodium azide. Store at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze thaw cycles.|
|Precautions||Anti-TASP / LANCL2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes.|
|Cellular Location||Nucleus. Cytoplasm. Cell membrane Note=Localizes to the juxta-nuclear vesicles (PubMed:16979580) Associates with the cortical actin cytoskeleton (PubMed:16979580) Cholesterol depletion by methyl-beta-cyclodextrin causes partial dissociation from the cell membrane in vitro and an enhanced cell detachment from the matrix in vivo (PubMed:16979580). Membrane- association is important for the increased cellular sensitivity to an anticancer drug (adriamycin) (PubMed:16979580)|
|Tissue Location||Expressed in brain and testis.|
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