|Application ||IHC-P, E|
|Calculated MW||55154 Da|
|Dilution||ELISA (1 µg/ml), IHC-P (10 µg/ml)|
|Other Names||SERPING1, C1-inhibiting factor, C1IN, C1 Inh, C1-INH, C1INH, C1NH, C1 Inhibitor, HAE1, HAE2, Plasma protease C1 inhibitor, C1 esterase inhibitor, Serpin G1|
|Target/Specificity||Human SERPING1/C1INH/C1 Inhibitor|
|Reconstitution & Storage||PBS, 0.09% sodium azide Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||Anti-SERPING1 / C1 Inhibitor Antibody (clone KT28) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Activation of the C1 complex is under control of the C1- inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein.|
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