|Application ||IHC-P, E|
|Predicted||Human, Monkey, Bovine|
|Calculated MW||62236 Da|
|Dilution||ELISA, IHC-P (5 - 10 µg/ml)|
|Other Names||PTH2R, Parathyroid hormone 2 receptor, Parathyroid hormone receptor 2, PTH2 receptor, PTHR2, Hpth2 receptor|
|Target/Specificity||Human PTH2R / PTHR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||PBS, less than 0.1% sodium azide. Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.|
|Precautions||Anti-PTHR2 / PTH2R Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed abundantly in brain and pancreas. Also expressed in the testis.|
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