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Anti-HAMP / Hepcidin Antibody

Rabbit Anti Human Polyclonal Antibody

  • IHC-P - Anti-HAMP / Hepcidin Antibody  ALS17322
    Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P81172
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 9408 Da
Dilution IHC-P (1:200), WB (1:500 - 1:2000)
Additional Information
Gene ID 57817
Alias Symbol HAMP
Other Names HAMP, Hepcidin antimicrobial peptide, LEAP-1, LEAP1, HEPC, Hepcidin, HFE2B, PLTR, Putative liver tumor regressor
Target/Specificity Human HAMP / Hepcidin
Reconstitution & Storage PBS, 0.1% sodium azide, 50% glycerol Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PrecautionsAnti-HAMP / Hepcidin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HEPC, LEAP1
Function Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed:22306005).
Cellular Location Secreted.
Tissue Location Highest expression in liver and to a lesser extent in heart and brain. Low levels in lung, tonsils, salivary gland, trachea, prostate gland, adrenal gland and thyroid gland Secreted into the urine.
Research Areas
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$ 395.00
Cat# ALS17322
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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