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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   GPCR Antibodies   >   Anti-TLR3 Antibody (aa180-385, clone ABM24E5)    

Anti-TLR3 Antibody (aa180-385, clone ABM24E5)

Rat Anti Mouse Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, Flo
Primary Accession O15455
Predicted Human, Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2b,k
Clone Names ABM24E5
Calculated MW 103829 Da
Dilution Flo, IHC-P (10 µg/ml), WB
Additional Information
Gene ID 7098
Alias Symbol TLR3
Other Names TLR3, CD283, Toll-like receptor 3, CD283 antigen, IIAE2
Reconstitution & Storage PBS, 0.05% sodium azide. Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PrecautionsAnti-TLR3 Antibody (aa180-385, clone ABM24E5) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TLR3
Function Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.
Cellular Location Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome membrane
Tissue Location Expressed at high level in placenta and pancreas. Also detected in CD11c+ immature dendritic cells. Only expressed in dendritic cells and not in other leukocytes, including monocyte precursors. TLR3 is the TLR that is expressed most strongly in the brain, especially in astrocytes, glia, and neurons.
Research Areas
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$ 395.00
Cat# ALS17349
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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