Anti-RP105 / CD180 Antibody (Internal)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | Q99467 |
Predicted | Human, Mouse, Monkey |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 74179 Da |
Dilution | IHC-P (1:100), WB (1:500 - 1:1000) |
Gene ID | 4064 |
---|---|
Alias Symbol | CD180 |
Other Names | CD180, CD180 antigen, Lymphocyte antigen 64, Ly78, LY64, CD180 molecule, RP105 |
Target/Specificity | Recognizes endogenous levels of CD180 protein. |
Reconstitution & Storage | PBS, pH 7.3, 0.01% sodium azide, 30% glycerol. Store at -20°C. Aliquot to avoid freeze/thaw cycles. |
Precautions | Anti-RP105 / CD180 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CD180 |
---|---|
Synonyms | LY64, RP105 |
Function | May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF- kappa-B activation. Also involved in the life/death decision of B-cells (By similarity). |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells |
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