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Anti-SPN / CD43 Antibody (clone DF-T1)

Mouse Anti Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, Flo
Primary Accession P16150
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG1,k
Clone Names DF-T1
Calculated MW 40322 Da
Dilution Flo, IHC-P (10 µg/ml)
Additional Information
Gene ID 6693
Alias Symbol SPN
Other Names SPN, GPL115, Leukosialin, Leukocyte sialoglycoprotein, Galactoglycoprotein, GALGP, Sialophorin, LSN, CD43, CD43 antigen
Target/Specificity Human SPN / CD43
Reconstitution & Storage PBS, 0.05% sodium azide. Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PrecautionsAnti-SPN / CD43 Antibody (clone DF-T1) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPN
Synonyms CD43
Function One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas
Research Areas
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$ 395.00
Cat# ALS17385
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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