|Application ||WB, IHC-P, IF, ICC, IP|
|Calculated MW||196436 Da|
|Dilution||ICC (1:100 - 1:500), IF (1:100 - 1:500), IHC-P (1:100), IP (1:10 - 1:100), WB (1:500 - 1:1000)|
|Other Names||MAST2, KIAA0807, MTSSK, RP4-533D7.1, MAST205|
|Target/Specificity||Recognizes endogenous levels of MAST2 protein.|
|Reconstitution & Storage||PBS, pH 7.3, 0.01% sodium azide, 30% glycerol. Store at -20°C. Aliquot to avoid freeze/thaw cycles.|
|Precautions||Anti-MAST205 / MAST2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Recruited to the sub-membranous area on interaction with CDHR2|
|Tissue Location||Abundant in the testis.|
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