|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat, Monkey|
|Calculated MW||81836 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:1000)|
|Other Names||SLC6A15, Orphan transporter v7-3, Transporter v7-3, NTT73, SBAT1, B0AT2, Hv7-3, V7-3|
|Target/Specificity||Recognizes endogenous levels of SBAT1 protein.|
|Reconstitution & Storage||PBS, pH 7.3, 0.01% sodium azide, 30% glycerol. Store at -20°C. Aliquot to avoid freeze/thaw cycles.|
|Precautions||Anti-SLC6A15 / SBAT1 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||B0AT2, NTT73, SBAT1|
|Function||Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Almost exclusively expressed in the brain.|
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