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Anti-CACNA1E / Cav2.3 Antibody (Internal)

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15878
Predicted Human, Mouse, Rat, Rabbit
Host Rabbit
Clonality Polyclonal
Calculated MW 261731 Da
Dilution IHC-P (1:100), WB (1:500 - 1:1000)
Additional Information
Gene ID 777
Alias Symbol CACNA1E
Other Names CACNA1E, BII, Brain calcium channel II, Cav2.3, CACNL1A6, Alpha 1e, CACH6, Cchra1
Target/Specificity Recognizes endogenous levels of Cav2.3 protein.
Reconstitution & Storage PBS, pH 7.3, 0.01% sodium azide, 30% glycerol. Store at -20°C. Aliquot to avoid freeze/thaw cycles.
PrecautionsAnti-CACNA1E / Cav2.3 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CACH6, CACNL1A6
Function Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel, and partially by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), omega- conotoxin-GVIA (omega-CTx-GVIA), and omega-agatoxin-IVA (omega- Aga-IVA). Calcium channels containing alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Expressed in neuronal tissues and in kidney.
Research Areas
Citations (0)

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$ 395.00
Cat# ALS17436
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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