Anti-CNTNAP2 / CASPR2 Antibody (C-Terminus)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | Q9UHC6 |
Predicted | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 148167 Da |
Dilution | IHC-P (10 µg/ml), WB (0.5 - 1 µg/ml) |
Gene ID | 26047 |
---|---|
Alias Symbol | CNTNAP2 |
Other Names | CNTNAP2, AUTS15, CDFE, CASPR2, KIAA0868, PTHSL1, NRXN4 |
Target/Specificity | Endogenous levels of mouse and rat Caspr2. It is predicted to react with human Caspr2 according to sequence homology. Positive Control: mouse brain and rat brain. |
Reconstitution & Storage | Lyophilized from PBS, pH 7.4, 0.02% sodium azide. Store lyophilized at -20°C. The reconstituted product can be stored for short term at 4 °C or long term at -20 °C or below. Avoid freeze/thaw cycles. |
Precautions | Anti-CNTNAP2 / CASPR2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CNTNAP2 |
---|---|
Synonyms | CASPR2 {ECO:0000303|PubMed:10624965}, KI |
Function | Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction. |
Cellular Location | Membrane {ECO:0000250|UniProtKB:Q9CPW0}; Single- pass type I membrane protein. Cell projection, axon {ECO:0000250|UniProtKB:Q9CPW0}. Cell junction, paranodal septate junction {ECO:0000250|UniProtKB:Q9CPW0}. Note=Expressed in the juxtaparadonal region. {ECO:0000250|UniProtKB:Q9CPW0} |
Tissue Location | Predominantly expressed in nervous system. |
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