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Anti-CNTNAP2 / CASPR2 Antibody (C-Terminus)

Rabbit Anti Human Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q9UHC6
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 148167 Da
Dilution IHC-P (10 µg/ml), WB (0.5 - 1 µg/ml)
Additional Information
Gene ID 26047
Alias Symbol CNTNAP2
Other Names CNTNAP2, AUTS15, CDFE, CASPR2, KIAA0868, PTHSL1, NRXN4
Target/Specificity Endogenous levels of mouse and rat Caspr2. It is predicted to react with human Caspr2 according to sequence homology. Positive Control: mouse brain and rat brain.
Reconstitution & Storage Lyophilized from PBS, pH 7.4, 0.02% sodium azide. Store lyophilized at -20°C. The reconstituted product can be stored for short term at 4 °C or long term at -20 °C or below. Avoid freeze/thaw cycles.
PrecautionsAnti-CNTNAP2 / CASPR2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNTNAP2
Synonyms CASPR2 {ECO:0000303|PubMed:10624965}, KI
Function Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction.
Cellular Location Membrane {ECO:0000250|UniProtKB:Q9CPW0}; Single- pass type I membrane protein. Cell projection, axon {ECO:0000250|UniProtKB:Q9CPW0}. Cell junction, paranodal septate junction {ECO:0000250|UniProtKB:Q9CPW0}. Note=Expressed in the juxtaparadonal region. {ECO:0000250|UniProtKB:Q9CPW0}
Tissue Location Predominantly expressed in nervous system.
Research Areas
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$ 467.50
Cat# ALS17453
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