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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   GPCR Antibodies   >   Anti-HTR1B / 5-HT1B Receptor Antibody (Cytoplasmic Domain)   

Anti-HTR1B / 5-HT1B Receptor Antibody (Cytoplasmic Domain)

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P28222
Predicted Human, Mouse, Rat, Rabbit, Hamster, Pig, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 43568 Da
Dilution IHC-P (7 µg/ml)
Additional Information
Gene ID 3351
Alias Symbol HTR1B
Other Names HTR1B, 5-HT-1B, 5-HT-1D-beta, 5-HT1B, 5-HT1b receptor, 5-HT1DB, 5HT1B Receptor, HTR1DB, Serotonin 5-HT-1b receptor, Serotonin receptor 1B, Serotonin 1b receptor, HTR1D2, Serotonin 1D beta receptor
Target/Specificity Human 5HT1B Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Immunoaffinity purified
PrecautionsAnti-HTR1B / 5-HT1B Receptor Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HTR1B
Synonyms HTR1DB
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Detected in cerebral artery smooth muscle cells (at protein level). Detected in brain cortex, striatum, amygdala, medulla, hippocampus, caudate nucleus and putamen
Research Areas
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$ 395.00
Cat# ALS17527
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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