|Predicted||Human, Mouse, Rat, Monkey, Horse|
|Calculated MW||171518 Da|
|Dilution||IHC-P (20 µg/ml)|
|Other Names||ADGRB3, KIAA0550, BAI3|
|Target/Specificity||Human BAI3. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ABCA13 (50%).|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-ADGRB3 / BAI3 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity (By similarity). Promotes myoblast fusion through ELMO/DOCK1 (PubMed:24567399).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Strongly expressed in brain. Also detected in heart. Reduced expression in some glioblastoma cell lines|
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