|Calculated MW||72621 Da|
|Dilution||IHC-P (2.5 µg/ml)|
|Other Names||ADGRE3, EGF-like module receptor 3, EMR3|
|Target/Specificity||Human EMR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-ADGRE3 / EMR3 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor probably involved in myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of momocytes- derived macrophages and activated neutrophils.|
|Cellular Location||EGF-like module-containing mucin-like hormone receptor-like 3: Cell membrane; Multi-pass membrane protein EGF-like module-containing mucin-like hormone receptor-like 3 subunit alpha: Secreted, extracellular space. Note=A soluble form is also detected (alpha subunit)|
|Tissue Location||Displays a predominantly leukocyte-restricted expression, with highest levels in neutrophils, monocytes and macrophages|
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