|Predicted||Human, Mouse, Rabbit, Chicken, Horse, Dog|
|Calculated MW||40055 Da|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||PTGFR, PGF receptor, PGF2-alpha receptor, Prostaglandin F receptor (FP), FP, PGF2 alpha receptor, Prostaglandin F receptor, Prostanoid FP receptor|
|Target/Specificity||Human PTGFR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-FP / PTGFR Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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