|Application ||WB, IHC-P, E|
|Calculated MW||22175 Da|
|Dilution||ELISA (1:16000), IHC-P (2.5 µg/ml), WB (1:16000, 0.1 - 0.3 µg/ml)|
|Other Names||GPX4, GPx-4, MCSP, SnPHGPx, Phospholipid hydroperoxidase, SnGPx, Glutathione peroxidase 4, GSHPx-4, PHGPx|
|Target/Specificity||Human GPX4. This antibody is expected to recognise isoform A (NP_002076.2) and isoform C (NP_001034937.1).|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-GPX4 / MCSP Antibody (aa184-196) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage (By similarity).|
|Cellular Location||Isoform Mitochondrial: Mitochondrion.|
|Tissue Location||Present primarily in testis.|
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