|Application ||WB, IHC-P, IF, IP|
|Predicted||Human, Hamster, Monkey, Pig|
|Calculated MW||23409 Da|
|Dilution||IF, IHC-P (20 µg/ml), IP, WB (1:1000)|
|Other Names||BAK1, Apoptosis regulator BAK, BAK, BCL2L7, Bcl-2-like protein 7, BCL2-antagonist/killer 1, Bcl2-L-7, BCL2-like 7 protein, CDN1, Pro-apoptotic protein BAK, BAK-LIKE|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-BAK1 / BAK Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BAK, BCL2L7, CDN1|
|Function||In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti- apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.|
|Cellular Location||Mitochondrion membrane; Single-pass membrane protein|
|Tissue Location||Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle|
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