|Application ||WB, IHC-P, IHC-F, IP, Flo|
|Calculated MW||24341 Da|
|Dilution||Flo (1:10 - 1:25), IHC-Fr, IHC-P (10 µg/ml), IP, WB|
|Other Names||CD53, CD53 antigen, CD53 molecule, CD53 tetraspan antigen, Cell surface antigen, Leukocyte surface antigen CD53, Transmembrane glycoprotein, Tetraspanin-25, Tspan-25, CD53 glycoprotein, Cell surface glycoprotein CD53, MOX44, TSPAN25|
|Reconstitution & Storage||Protein G purified|
|Precautions||Anti-CD53 Antibody (clone MEM-53) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity).|
|Cellular Location||Cell membrane. Cell junction. Membrane; Multi-pass membrane protein Note=Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes|
|Tissue Location||B-cells, monocytes, macrophages, neutrophils, single (CD4 or CD8) positive thymocytes and peripheral T-cells|
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