|Application ||WB, IHC-P|
|Calculated MW||22878 Da|
|Dilution||IHC-P (10 µg/ml), WB (1:500 - 1:1000)|
|Other Names||ARTN, ENOVIN, EVN, Neurotrophic factor, Artemin, Neublastin|
|Target/Specificity||Internal sequence [GPGSRARAAGARGC] of human Artemin|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-ARTN / Artemin Antibody (aa127-140) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue.|
|Tissue Location||Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain.|
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