|Predicted||Human, Mouse, Rat, Monkey, Pig, Bovine|
|Calculated MW||30037 Da|
|Dilution||IHC-P (2.5 - 5 µg/ml)|
|Other Names||COMT, Catechol O-methyltransferase, Catechol-O-methyltransferase|
|Target/Specificity||Human COMT. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-COMT Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.|
|Cellular Location||Isoform Soluble: Cytoplasm.|
|Tissue Location||Brain, liver, placenta, lymphocytes and erythrocytes|
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