|Calculated MW||83284 Da|
|Dilution||IHC-P (5 - 7.5 µg/ml)|
|Other Names||PIGR, Poly-Ig receptor|
|Target/Specificity||Human PIGR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-PIGR Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
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